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Chapter 8 Part 1

             Mitosis
Cell Division and Reproduction
Chromosomes become visible
         during cell division
A karyotype displays the
  chromosomes
• Karyotype
   – Display of the
     chromosomes
   – 23 pairs of chromosomes
   – 46 total chromosomes
   – One member of each pair
     comes from the father, the
     other member comes from
     the mother
• Autosomes
  – Have nothing to do with gender
  – 22 pairs
• Sex chromosomes
  – Determines gender
  – XY is male
  – XX is female
• Homologous pair
  – Pair of autosomal chromosomes
  – Look alike
  – Carry genes for the same trait (earlobe, hairline,
    finger length)
• Sister chromatids
  – Duplicated chromosome required for mitosis
• Centromere
  – Holds together sister chromatids
• Kinetochores
  – Protein complexes at centromere where spindle fiber
    attaches during cell division
The eukaryotic cell cycle has a set series of stages
• Cell cycle
   – Series of stages of cell growth and
     division
• Interphase
   – Time between cell division
       • G1 Stage
           – Recovery from division
           – Decides whether to divide or not
                 » Enters G0 if it is not going to
                     divide where it will continue
                     normal processes
           – If it is going to divide, it doubles in
             size, double organelles, accumulates
             molecules needed for DNA synthesis
       • S Stage
           – DNA replicated resulting in sister
             chromatids
       • G2 Stage
           – Organelle replication continues
           – Makes proteins (microtubules)
             needed for cell division
M stage (mitosis)
• Cell division
• Chromosomes
  divided between 2
  cells
• Cytokinesis
  – Division of cytoplasm
Mitosis maintains the chromosome
             number
Following mitosis, daughter cells
  have the same chromosome
  count as the parent cell
• Parent cell
   – Original cell
• Daughter cells
   – 2 new cells
• When cells enter M stage, it has
  sister chromatids (duplicated
  chromosomes)
• Animal cell are diploid (2n)
  throughout mitosis (chromosomes
  are in pairs)
• Some protists and fungi are
  haploid (n) before and after
  mitosis
The spindle apparatus
• Centrosome
  – Divides at the start of
    nuclear division
  – Produce spindle fibers,
    which assist
    separation of the
    chromatids as they
    move to opposite
    poles
Mitosis has a set series of phases
Early prophase
• Centrosomes divided
• Chromatin condensing into chomosomes
• Nuclear envelope fragmenting
Prophase
• Nucleolus disappeared
• Duplicated chromosomes (sister chromatids)
  visible
• Centosomes begin moving apart
• Spindle is in the process of forming
Early metaphase
• Each duplicated chromosomes attached
  to the spindle apparatus
• Spindle fibers stretch from each pole
Metaphase
• Centromeres of duplicated chromosomes
  are aligned at equator
• Kinetochores attach sister chromatids to
  spindle fibers that come from opposite
  poles
Anaphase
• Sister chromatids part and become
  daughter chromosomes that are pulled
  toward the poles
Telophase
• Daughter cells are forming
• Nuclear envelopes and nucleoli reappear
• Chromosomes become chromatin
Contribution of the Cell Cycle to
          Human Health
Cell division allows a fertilized egg to
 develop into a newborn and is also
 important in repairing damage to your
 body like broken bones and cuts.
Cytokinesis divides the cytoplasm
Animal cell cytokinesis
• Cleavage furrow
  forms between the
  two daughter cells
• Furrow deepens
  when the contractile
  ring forms between
  cells and continues to
  tighten
• 2 independent
  daughter cells result
Plant cell cytokinesis
• A new plasma membrane (cell plate)
  comes between the new cells
• The new membrane releases molecules
  that form a new cell wall between the new
  cells
http://media.pearsoncmg.com/bc/bc_0media_bio

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Bio 100 Chapter 8 part 1

  • 1. Chapter 8 Part 1 Mitosis Cell Division and Reproduction
  • 2. Chromosomes become visible during cell division A karyotype displays the chromosomes • Karyotype – Display of the chromosomes – 23 pairs of chromosomes – 46 total chromosomes – One member of each pair comes from the father, the other member comes from the mother
  • 3. • Autosomes – Have nothing to do with gender – 22 pairs • Sex chromosomes – Determines gender – XY is male – XX is female • Homologous pair – Pair of autosomal chromosomes – Look alike – Carry genes for the same trait (earlobe, hairline, finger length)
  • 4. • Sister chromatids – Duplicated chromosome required for mitosis • Centromere – Holds together sister chromatids • Kinetochores – Protein complexes at centromere where spindle fiber attaches during cell division
  • 5. The eukaryotic cell cycle has a set series of stages • Cell cycle – Series of stages of cell growth and division • Interphase – Time between cell division • G1 Stage – Recovery from division – Decides whether to divide or not » Enters G0 if it is not going to divide where it will continue normal processes – If it is going to divide, it doubles in size, double organelles, accumulates molecules needed for DNA synthesis • S Stage – DNA replicated resulting in sister chromatids • G2 Stage – Organelle replication continues – Makes proteins (microtubules) needed for cell division
  • 6. M stage (mitosis) • Cell division • Chromosomes divided between 2 cells • Cytokinesis – Division of cytoplasm
  • 7. Mitosis maintains the chromosome number Following mitosis, daughter cells have the same chromosome count as the parent cell • Parent cell – Original cell • Daughter cells – 2 new cells • When cells enter M stage, it has sister chromatids (duplicated chromosomes) • Animal cell are diploid (2n) throughout mitosis (chromosomes are in pairs) • Some protists and fungi are haploid (n) before and after mitosis
  • 8. The spindle apparatus • Centrosome – Divides at the start of nuclear division – Produce spindle fibers, which assist separation of the chromatids as they move to opposite poles
  • 9. Mitosis has a set series of phases Early prophase • Centrosomes divided • Chromatin condensing into chomosomes • Nuclear envelope fragmenting Prophase • Nucleolus disappeared • Duplicated chromosomes (sister chromatids) visible • Centosomes begin moving apart • Spindle is in the process of forming
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  • 11. Early metaphase • Each duplicated chromosomes attached to the spindle apparatus • Spindle fibers stretch from each pole Metaphase • Centromeres of duplicated chromosomes are aligned at equator • Kinetochores attach sister chromatids to spindle fibers that come from opposite poles
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  • 13. Anaphase • Sister chromatids part and become daughter chromosomes that are pulled toward the poles Telophase • Daughter cells are forming • Nuclear envelopes and nucleoli reappear • Chromosomes become chromatin
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  • 15. Contribution of the Cell Cycle to Human Health Cell division allows a fertilized egg to develop into a newborn and is also important in repairing damage to your body like broken bones and cuts.
  • 16. Cytokinesis divides the cytoplasm Animal cell cytokinesis • Cleavage furrow forms between the two daughter cells • Furrow deepens when the contractile ring forms between cells and continues to tighten • 2 independent daughter cells result
  • 17. Plant cell cytokinesis • A new plasma membrane (cell plate) comes between the new cells • The new membrane releases molecules that form a new cell wall between the new cells